Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.55 |
| ▸ | RAB9A | P51151 | 15/20 | 0.55 |
| ▸ | PKM | P14618 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273690 | 1.00 | NPC1 (0.55) | NPC1RAB9APKMGAAPOLB | |
| SCHEMBL265842 | 0.90 | NPC1 (0.53) | NPC1RAB9APKMGAAPOLB | |
| SCHEMBL273516 | 0.90 | NPC1 (0.53) | NPC1RAB9APKMGAAPOLB | |
| SCHEMBL269535 | 0.89 | MEN1 (0.51) | NPC1RAB9APKMGAAPOLB | |
| SCHEMBL274295 | 0.89 | MEN1 (0.51) | NPC1RAB9APKMGAAPOLB | |
| SCHEMBL265191 | 0.86 | PKM (0.71) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL265192 | 0.86 | PKM (0.71) | NPC1RAB9APKMPOLBMAPT | |
| Hydrochloric Acid SCHEMBL265638 | 0.85 | PKM (0.69) | NPC1RAB9APKMPOLBMAPT | |
| Hydrochloric Acid SCHEMBL265639 | 0.85 | PKM (0.69) | NPC1RAB9APKMPOLBMAPT | |
| SCHEMBL273860 | 0.84 | MAPT (0.69) | NPC1RAB9APKMGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1614676-A1 | COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-01-11 | — | — | EP | disclosed |