Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 18/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660331 | 0.86 | TXNRD1 (0.44) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL26931313 | 0.78 | TXNRD1 (0.52) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL16729351 | 0.76 | TXNRD1 (0.51) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL621047 | 0.72 | TXNRD1 (0.54) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL14800646 | 0.69 | GAA (0.45) | HTT | |
| SCHEMBL16648934 | 0.69 | TXNRD1 (0.53) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL1162351 | 0.68 | TXNRD1 (0.52) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL4308799 | 0.68 | MAPT (0.65) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL5832677 | 0.68 | TXNRD1 (0.63) | TXNRD1MAPTRAB9AGSR | |
| SCHEMBL1428159 | 0.68 | TXNRD1 (0.58) | TXNRD1S1PR4MAPTS1PR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023238065-A1 | NITROGEN CONTAINING CONDENSED 2,3-DIHYDROQUINAZOLINONE COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-12-14 | — | — | WO | disclosed |