Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.32 |
| ▸ | SQLE | Q14534 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9969645 | 0.86 | SQLE (0.31) | SQLE | |
| SCHEMBL14530067 | 0.80 | LSS (0.45) | S1PR2S1PR1S1PR3S1PR5KDM4C | |
| SCHEMBL15901569 | 0.79 | CA12 (0.37) | KDM4CKDM5APHF8ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL22771967 | 0.77 | CA12 (0.35) | KDM5ADNM1ALDH1A1ALDH2CA12 | |
| SCHEMBL15228459 | 0.77 | SQLE (0.53) | GGPS1SQLEALDH1A1 | |
| SCHEMBL11685165 | 0.75 | DNM1 (0.38) | S1PR2S1PR1S1PR3S1PR5KDM4C | |
| SCHEMBL15228332 | 0.75 | SQLE (0.51) | GGPS1SQLEALDH1A1 | |
| SCHEMBL1462685 | 0.71 | — | — | |
| SCHEMBL5961343 | 0.71 | — | — | |
| SCHEMBL29066997 | 0.71 | DNM1 (0.41) | KDM4CKDM5APHF8DNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399332-A1 | IMIDAZO[1,2-a]PYRAZINE OR PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND USE THEREOF | TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED (CN) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399332-A1 | IMIDAZO[1,2-a]PYRAZINE OR PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND USE THEREOF | CYP2D6, UGT1A1, TPMT | S1PR2 1565/4885S1PR1 1381/4885S1PR3 1244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.