Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | ERN1 | O75460 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12217607 | 0.86 | MKNK1 (0.60) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14506746 | 0.83 | MKNK1 (0.61) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11327666 | 0.83 | ERN1 (0.65) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1423492 | 0.83 | NPC1 (0.64) | CYP3A4ALDH1A1CYP1A2KDM4ENPC1 | |
| Bromide SCHEMBL11325605 | 0.81 | ERN1 (0.63) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27812061 | 0.80 | NPY5R (0.60) | CYP2A6 | |
| SCHEMBL12117595 | 0.79 | ERN1 (0.51) | MKNK1MKNK2CYP19A1ERN1CYP2A6 | |
| SCHEMBL12326414 | 0.79 | CYP2A6 (0.54) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11371958 | 0.79 | MKNK1 (0.62) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL4791110 | 0.79 | CYP11B2 (0.56) | MKNK1MKNK2CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |