Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314678 | 1.00 | MAPT (0.54) | MAPTKDM4ECES2ALDH1A1CA12 | |
| SCHEMBL2704158 | 0.83 | ESR1 (0.50) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL16476581 | 0.83 | ESR1 (0.50) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL2315055 | 0.83 | ESR1 (0.50) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL2316293 | 0.81 | ALDH1A1 (0.61) | MAPTKDM4EALDH1A1TSHRLMNA | |
| SCHEMBL1656386 | 0.81 | ESR1 (0.56) | MAPTKDM4ECES2ALDH1A1CA12 | |
| SCHEMBL3859431 | 0.81 | ESR1 (0.56) | MAPTKDM4ECES2ALDH1A1CA12 | |
| SCHEMBL1656388 | 0.81 | ESR1 (0.56) | MAPTKDM4ECES2ALDH1A1CA12 | |
| SCHEMBL2695442 | 0.74 | KMT2A (0.68) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL15053133 | 0.74 | KMT2A (0.68) | MAPTKDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402081-A1 | AMMONIA DECOMPOSITION CATALYST | Hitachi Zosen Corporation (JP) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010098245-A1 | AMMONIA DECOMPOSITION CATALYST | 日立造船株式会社 (JP) | 2010-09-02 | — | — | WO | disclosed |