Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26938695 | 1.00 | DRD2 (0.42) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL21105462 | 0.88 | DRD2 (0.43) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL29612752 | 0.88 | DRD2 (0.43) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL21107184 | 0.88 | DRD2 (0.43) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL29612716 | 0.88 | DRD2 (0.43) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL25982227 | 0.88 | DRD2 (0.43) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL29612718 | 0.88 | DRD2 (0.43) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL21107182 | 0.87 | DRD2 (0.42) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL21105461 | 0.87 | DRD2 (0.42) | DRD2BTKGAAKDM1AMAOB | |
| SCHEMBL29612744 | 0.87 | DRD2 (0.42) | DRD2BTKGAAKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | DRD2 4346/4885BTK 27/4885GAA 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.