Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 5/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26940757 | 1.00 | NLRP3 (0.52) | NLRP3CHRM1IL1BTNFKDM4E | |
| SCHEMBL26938426 | 1.00 | NLRP3 (0.52) | NLRP3CHRM1IL1BTNFKDM4E | |
| SCHEMBL26940807 | 0.85 | NLRP3 (0.39) | NLRP3CHRM1IL1BTNFKDM4E | |
| SCHEMBL26938431 | 0.85 | NLRP3 (0.39) | NLRP3CHRM1IL1BTNFKDM4E | |
| SCHEMBL26940810 | 0.85 | NLRP3 (0.39) | NLRP3CHRM1IL1BTNFKDM4E | |
| SCHEMBL26938433 | 0.83 | NLRP3 (0.52) | NLRP3CHRM1IL1BTNF | |
| SCHEMBL26938423 | 0.82 | NLRP3 (0.51) | NLRP3CHRM1 | |
| SCHEMBL26938415 | 0.74 | NLRP3 (0.49) | NLRP3IL1BKDM4EALDH1A1 | |
| SCHEMBL26938399 | 0.73 | NLRP3 (0.62) | NLRP3CHRM1IL1BTNF | |
| SCHEMBL26940373 | 0.73 | NLRP3 (0.62) | NLRP3CHRM1IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |