Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 11/20 | 0.62 |
| ▸ | CDK2 | P24941 | 11/20 | 0.62 |
| ▸ | CCND1 | P24385 | 9/20 | 0.62 |
| ▸ | CDK6 | Q00534 | 9/20 | 0.62 |
| ▸ | CDK4 | P11802 | 7/20 | 0.62 |
| ▸ | CDK1 | P06493 | 6/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.62 |
| ▸ | CCND3 | P30281 | 6/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.62 |
| ▸ | CDK9 | P50750 | 6/20 | 0.62 |
| ▸ | CDK7 | P50613 | 5/20 | 0.62 |
| ▸ | CCNH | P51946 | 5/20 | 0.62 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26941951 | 0.84 | CDK2 (0.46) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26941920 | 0.84 | CDK2 (0.56) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26941973 | 0.83 | CCNE1 (0.65) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26942400 | 0.83 | CDK2 (0.55) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26918876 | 0.83 | CCNE1 (0.54) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26941974 | 0.82 | CDK2 (0.61) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26946581 | 0.82 | CDK2 (0.53) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26942572 | 0.81 | CCNE1 (0.51) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26941918 | 0.81 | CCNE1 (0.49) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26919238 | 0.80 | CCR6 (0.48) | CCNE1CDK2CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |