Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 16/20 | 0.65 |
| ▸ | CDK2 | P24941 | 16/20 | 0.65 |
| ▸ | CCND1 | P24385 | 12/20 | 0.65 |
| ▸ | CDK6 | Q00534 | 12/20 | 0.65 |
| ▸ | CDK1 | P06493 | 10/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 10/20 | 0.65 |
| ▸ | CDK4 | P11802 | 9/20 | 0.65 |
| ▸ | CCND3 | P30281 | 9/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.65 |
| ▸ | CDK7 | P50613 | 3/20 | 0.65 |
| ▸ | CDK9 | P50750 | 3/20 | 0.65 |
| ▸ | CCNH | P51946 | 3/20 | 0.65 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.65 |
| ▸ | ULK1 | O75385 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449148 | 0.87 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22900798 | 0.87 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977480 | 0.85 | CCNE1 (0.75) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL26941950 | 0.84 | CDK2 (0.65) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL26941952 | 0.83 | CCNE1 (0.62) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL26941552 | 0.83 | ULK1 (0.67) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977071 | 0.81 | CCNE1 (0.69) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977326 | 0.81 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30449106 | 0.81 | CCNE1 (0.69) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30906769 | 0.81 | CCNE1 (0.66) | CCNE1CDK2CCND1CDK6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |