SCHEMBL26944293

SCHEMBL26944293

N#CSc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
USP8 P40818 1/20 0.41
USP5 P45974 1/20 0.41
USP4 Q13107 1/20 0.41
USP7 Q93009 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPK1 P28482 1/20 0.33
AHR P35869 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CTSK P43235 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6091835 0.82 GAA (0.50) USP2USP8USP5USP4USP7
SCHEMBL11367939 0.79 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL17378572 0.75 TP53 (0.42) USP2USP8USP5USP4USP7
SCHEMBL12273316 0.75 ITGB2 (0.46) USP2USP8USP5USP4USP7
SCHEMBL4678827 0.73 HPGD (0.34) USP2USP8USP5USP4USP7
SCHEMBL9940012 0.73 TRPV4 (0.41) USP2USP8USP5USP4USP7
SCHEMBL13992668 0.72 AR (0.54) USP2USP8USP5USP4USP7
SCHEMBL14257325 0.72 USP2 (0.35) USP2USP8USP5USP4USP7
SCHEMBL11874781 0.72 PDE7A (0.53) USP2USP8USP5USP4USP7
SCHEMBL11862552 0.72 HSD17B10 (0.46) USP2USP8USP5USP4USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399942-A1 FLUORESCENT DYE OIL TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-12-14 US disclosed