Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851747 | 0.86 | PIK3C3 (0.38) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL26944748 | 0.85 | CSF1R (0.35) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL21824003 | 0.84 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL21824005 | 0.84 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL26944686 | 0.82 | CSF1R (0.35) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL21851762 | 0.79 | CSF1R (0.34) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL21823992 | 0.79 | CSF1R (0.59) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL21823993 | 0.79 | CSF1R (0.59) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL21851727 | 0.79 | CSF1R (0.34) | CSF1RPDGFRAPDGFRBFLT3LCK | |
| SCHEMBL26944710 | 0.77 | CSF1R (0.34) | CSF1RPDGFRAPDGFRBFLT3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-B1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO LTD (CN) | 2023-12-13 | — | — | EP | disclosed |