Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26327649 | 0.84 | TMPRSS2 (0.33) | TMPRSS2 | |
| SCHEMBL12454229 | 0.81 | POLRMT (0.38) | TMPRSS2POLRMT | |
| SCHEMBL24606306 | 0.81 | TMPRSS2 (0.41) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL25916466 | 0.79 | TMPRSS2 (0.32) | TMPRSS2RIPK1 | |
| Obeldesivir SCHEMBL27216326 | 0.79 | TMPRSS2 (0.49) | TMPRSS2POLRMTRIPK1 | |
| Obeldesivir SCHEMBL23959875 | 0.79 | TMPRSS2 (0.49) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL25918408 | 0.78 | TMPRSS2 (0.36) | TMPRSS2RIPK1 | |
| SCHEMBL24789693 | 0.78 | POLRMT (0.38) | TMPRSS2POLRMT | |
| SCHEMBL29566128 | 0.78 | TMPRSS2 (0.32) | TMPRSS2RIPK1 | |
| SCHEMBL20144212 | 0.77 | TMPRSS2 (0.37) | TMPRSS2POLRMTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239665-A1 | METHODS FOR TREATMENT OF VIRAL INFECTIONS INCLUDING SARS-COV-2 | GILEAD SCIENCES, INC. (US) | 2023-12-14 | — | — | WO | disclosed |