SCHEMBL26945313

SCHEMBL26945313

CC(C)(C)OC(=O)N1CCCNc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.54
KDM1A O60341 1/20 0.47
AVPR1A P37288 2/20 0.47
AVPR2 P30518 1/20 0.47
HDAC1 Q13547 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
BCHE P06276 1/20 0.43
HSD17B3 P37058 1/20 0.41
HSD11B1 P28845 1/20 0.39
GPR119 Q8TDV5 2/20 0.38
UCHL1 P09936 1/20 0.38
BUB1 O43683 1/20 0.37
EPHX2 P34913 1/20 0.37
SCN5A Q14524 1/20 0.37
SCN9A Q15858 1/20 0.37
BRD4 O60885 1/20 0.37
AKT1 P31749 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505992 0.92 MAPK1 (0.60) MAPK1KDM1AAVPR1AAVPR2HDAC1
SCHEMBL975814 0.92 MAPK1 (0.60) MAPK1KDM1AAVPR1AAVPR2HDAC1
SCHEMBL6583411 0.83 MAPK1 (0.49) MAPK1KDM1AAVPR1AHDAC1HDAC6
SCHEMBL3972182 0.78 AVPR1A (0.50) AVPR1AAVPR2HSD17B3HSD11B1
SCHEMBL31033163 0.77 BRD4 (0.52) MAPK1KDM1AHDAC1HDAC6BCHE
SCHEMBL3127747 0.76 NOTUM (0.63)
SCHEMBL29476005 0.76 NOTUM (0.63)
SCHEMBL5795681 0.75 NOTUM (0.57) KDM1AAVPR1AAVPR2
SCHEMBL7997935 0.74 SMN1; SMN2 (0.61) MAPK1BRD4
SCHEMBL29960283 0.74 KDM1A (0.48) MAPK1KDM1AHDAC1HDAC6BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023239227-A1 NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 사피엔스바이오 2023-12-14 WO disclosed