SCHEMBL2694591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4156875	0.82	KMT2A (0.63)	KMT2AMEN1ALDH1A1TSHRMAPT
	SCHEMBL28161168	0.81	MAPT (0.51)	KMT2AMEN1ALDH1A1TSHRMAPT
	SCHEMBL2102471	0.80	KMT2A (0.58)	CYP11B1KMT2AMEN1ALDH1A1TSHR
	SCHEMBL29035960	0.78	KMT2A (0.60)	KMT2AMEN1ALDH1A1TSHRMAPT
	SCHEMBL2881602	0.78	CYP11B1 (0.56)	CYP11B1KMT2AMEN1MAPTPOLB
	SCHEMBL3243743	0.78	CYP11B1 (0.56)	CYP11B1KMT2AMEN1TSHRPOLB
	SCHEMBL2694560	0.77	MEN1 (0.69)	CYP11B1KMT2AMEN1ALDH1A1TSHR
	SCHEMBL31254284	0.77	KMT2A (0.58)	KMT2AMEN1ALDH1A1TSHRMAPT
	SCHEMBL28647868	0.77	KMT2A (0.61)	KMT2AMEN1ALDH1A1TSHRMAPT
	SCHEMBL29638283	0.77	KMT2A (0.58)	KMT2AMEN1ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.