Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 7/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696843 | 1.00 | LMNA (0.42) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2696736 | 1.00 | LMNA (0.42) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL339731 | 1.00 | LMNA (0.42) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2694433 | 0.99 | S1PR4 (0.41) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL6240605 | 0.94 | SMN1; SMN2 (0.41) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL6241300 | 0.88 | METAP1 (0.38) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL17817569 | 0.88 | LMNA (0.55) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL25311982 | 0.86 | AKT1 (0.60) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL31365417 | 0.86 | AKT1 (0.60) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL29492658 | 0.86 | AKT1 (0.60) | LMNAESR1ADORA3CDC25AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9606126-B2 | Compositions and methods for membrane protein detergent stability screen | UNIVERSITY OF VIRGINA PATENT FOUNDATION (US) | 2017-03-28 | — | — | US | claimed |
| US-11740235-B2 | Model-membrane-based lipid transfer assays and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2023-08-29 | — | — | US | disclosed |
| US-20210055294-A1 | MODEL-MEMBRANE-BASED LIPID TRANSFER ASSAYS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2021-02-25 | — | — | US | disclosed |
| US-9606126-B2 | Compositions and methods for membrane protein detergent stability screen | UNIVERSITY OF VIRGINA PATENT FOUNDATION (US) | 2017-03-28 | — | — | US | disclosed |
| US-20170067904-A1 | COMPOSITIONS AND METHODS FOR MEMBRANE PROTEIN DETERGENT STABILITY SCREEN | UNIV VIRGINIA PATENT FOUNDATION (US) | 2017-03-09 | — | — | US | disclosed |
| US-20120108463-A1 | COMPOSITIONS AND METHODS FOR MEMBRANE PROTEIN DETERGENT STABILITY SCREEN | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-05-03 | — | — | US | disclosed |