⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26705617 | 0.84 | — | — | |
| SCHEMBL26712536 | 0.78 | — | — | |
| SCHEMBL22939481 | 0.64 | — | — | |
| SCHEMBL26948343 | 0.63 | — | — | |
| SCHEMBL25141236 | 0.60 | MAPT (0.30) | — | |
| SCHEMBL21038238 | 0.58 | — | — | |
| SCHEMBL21119068 | 0.57 | — | — | |
| SCHEMBL26705614 | 0.57 | — | — | |
| SCHEMBL25930888 | 0.56 | — | — | |
| SCHEMBL19904961 | 0.55 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |