Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24475624 | 1.00 | HRH3 (0.36) | HRH3KCNH2CYP2D6L3MBTL3L3MBTL1 | |
| SCHEMBL24475409 | 0.88 | KDM4E (0.37) | HRH3KCNH2CYP2D6KDM4EPOLB | |
| SCHEMBL24475419 | 0.88 | KDM4E (0.37) | HRH3KCNH2CYP2D6KDM4EPOLB | |
| SCHEMBL20008983 | 0.85 | POLB (0.46) | HRH3ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL20009031 | 0.85 | POLB (0.46) | HRH3ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL20009046 | 0.85 | POLB (0.46) | HRH3ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL408516 | 0.79 | CHRNA7 (0.34) | HRH3KCNH2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL22565540 | 0.78 | L3MBTL3 (0.47) | KCNH2CYP2D6L3MBTL3L3MBTL1DRD2 | |
| SCHEMBL24837354 | 0.75 | KDM1A (0.35) | HRH3KCNH2CYP2D6ALDH1A1CHRNA7 | |
| SCHEMBL24453213 | 0.75 | HRH3 (0.36) | HRH3KCNH2CYP2D6ALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244918-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |