Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13860741 | 0.94 | CHRM5 (0.50) | CHRM5ADRA2CSIGMAR1ACHEHRH3 | |
| SCHEMBL14453909 | 0.92 | CHRM5 (0.41) | CHRM5ADRA2CACHEHRH3KCNH2 | |
| SCHEMBL24233173 | 0.90 | ACHE (0.44) | CHRM5ADRA2CACHEHRH3KCNH2 | |
| SCHEMBL10104076 | 0.90 | CHRM5 (0.56) | CHRM5ADRA2CACHEHRH3 | |
| SCHEMBL22520769 | 0.90 | CHRM5 (0.43) | CHRM5ADRA2CACHEHRH3KCNH2 | |
| SCHEMBL15242459 | 0.89 | CHRM5 (0.59) | CHRM5ADRA2CACHEHRH3 | |
| SCHEMBL24952740 | 0.86 | CHRM5 (0.50) | CHRM5ADRA2CSIGMAR1ACHEHRH3 | |
| SCHEMBL10092699 | 0.86 | CHRM5 (0.43) | CHRM5ADRA2CACHEHRH3KCNH2 | |
| SCHEMBL21477202 | 0.85 | CHRM5 (0.39) | CHRM5ADRA2CSIGMAR1ACHEHRH3 | |
| SCHEMBL10042371 | 0.85 | CHRM5 (0.59) | CHRM5ADRA2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |