⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904961 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL23265523 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL12395195 | 0.69 | PIK3CD (0.33) | — | |
| SCHEMBL27743701 | 0.61 | — | — | |
| SCHEMBL1698490 | 0.61 | MAPT (0.33) | — | |
| Hydrochloric Acid SCHEMBL992328 | 0.60 | PRKACA (0.34) | — | |
| Hydrochloric Acid SCHEMBL992326 | 0.60 | PRKACA (0.34) | — | |
| SCHEMBL18976352 | 0.59 | LMNA (0.30) | — | |
| SCHEMBL27152565 | 0.59 | PIK3CD (0.46) | — | |
| SCHEMBL29640103 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023237580-A1 | TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2023-12-14 | — | — | WO | disclosed |