Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23311954 | 0.77 | GSK3B (0.34) | METGSK3BHDAC1HDAC2 | |
| SCHEMBL1253531 | 0.75 | NPC1 (0.39) | METGSK3BHDAC1HDAC2MAOA | |
| SCHEMBL1577119 | 0.72 | — | — | |
| SCHEMBL1577120 | 0.72 | — | — | |
| SCHEMBL15511781 | 0.70 | MET (0.31) | METGSK3B | |
| SCHEMBL15511700 | 0.70 | MET (0.31) | METGSK3B | |
| SCHEMBL32681717 | 0.70 | MET (0.31) | METGSK3B | |
| SCHEMBL15511783 | 0.70 | MET (0.31) | METGSK3B | |
| SCHEMBL2286246 | 0.70 | MET (0.31) | METGSK3B | |
| SCHEMBL18727658 | 0.70 | ERN1 (0.43) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240253-A2 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |