Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507342 | 0.88 | SMN1; SMN2 (0.68) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL26467345 | 0.84 | CASP3 (0.64) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL18380903 | 0.84 | NPC1 (0.69) | CASP3SENP7SENP6SENP8NPC1 | |
| Hydrochloric Acid SCHEMBL8688433 | 0.82 | CASP3 (0.62) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL14075974 | 0.82 | NPC1 (0.53) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL3190505 | 0.81 | CASP3 (0.76) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL1660542 | 0.81 | NPC1 (0.67) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL26952117 | 0.81 | CASP3 (0.64) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL15080531 | 0.80 | NPC1 (0.68) | CASP3SENP7SENP6SENP8NPC1 | |
| SCHEMBL31319893 | 0.80 | CASP3 (0.59) | CASP3SENP7SENP6SENP8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236263-A1 | BENZOXAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-12-14 | — | — | WO | disclosed |