Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.45 |
| ▸ | STK3 | Q13188 | 2/20 | 0.45 |
| ▸ | STK4 | Q13043 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 7/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734920 | 1.00 | SGK1 (0.46) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL31735009 | 0.86 | LRRK2 (0.52) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL26953146 | 0.86 | LRRK2 (0.52) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL31735012 | 0.86 | SGK1 (0.57) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL26953278 | 0.86 | SGK1 (0.57) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL26953435 | 0.86 | SGK1 (0.44) | SGK1LRRK2STK3JAK2CDC7 | |
| SCHEMBL31734984 | 0.86 | SGK1 (0.44) | SGK1LRRK2STK3JAK2CDC7 | |
| SCHEMBL31735137 | 0.85 | LRRK2 (0.45) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL26953219 | 0.85 | LRRK2 (0.45) | SGK1LRRK2STK3STK4JAK2 | |
| SCHEMBL31735066 | 0.82 | JAK3 (0.55) | SGK1LRRK2STK3STK4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |