Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26274093 | 0.92 | CRBN (0.43) | CRBNDDB1POLBKMT2AGAA | |
| SCHEMBL5617171 | 0.86 | NPC1 (0.39) | CRBNDDB1POLBKMT2ADAGLA | |
| SCHEMBL18473550 | 0.84 | ALDH1A1 (0.40) | CRBNPOLBKMT2ACYP1A2DAGLA | |
| SCHEMBL19657857 | 0.84 | ALDH1A1 (0.40) | CRBNPOLBKMT2ACYP1A2DAGLA | |
| SCHEMBL9569047 | 0.84 | ALDH1A1 (0.40) | CRBNPOLBKMT2ACYP1A2DAGLA | |
| SCHEMBL6077509 | 0.84 | ALDH1A1 (0.40) | CRBNPOLBKMT2ACYP1A2DAGLA | |
| SCHEMBL4455145 | 0.84 | ALDH1A1 (0.40) | CRBNPOLBKMT2ACYP1A2DAGLA | |
| SCHEMBL18888511 | 0.81 | NPC1 (0.40) | CRBNDDB1POLBKMT2A | |
| SCHEMBL23436811 | 0.78 | ALDH1A1 (0.42) | CRBNPOLBKMT2ADAGLACCR2 | |
| SCHEMBL19157284 | 0.78 | ALDH1A1 (0.42) | CRBNPOLBKMT2ADAGLACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |