Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849587 | 0.90 | KMT2A (0.50) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL11637311 | 0.88 | KMT2A (0.47) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL18218 | 0.87 | KMT2A (0.47) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL17442 | 0.85 | KMT2A (0.46) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL18047923 | 0.85 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL16835 | 0.84 | KMT2A (0.44) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL18334492 | 0.81 | KMT2A (0.41) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL7863108 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL15362867 | 0.80 | KMT2A (0.37) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 | |
| SCHEMBL30140023 | 0.79 | KMT2A (0.42) | KMT2ASMN1; SMN2CYP2C19STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |