Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442 | 0.98 | KMT2A (0.46) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL16835 | 0.97 | KMT2A (0.44) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL7849587 | 0.90 | KMT2A (0.50) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL11637311 | 0.89 | KMT2A (0.47) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL26960 | 0.87 | KMT2A (0.44) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL8598041 | 0.87 | CYP3A4 (0.46) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL15979027 | 0.87 | KMT2A (0.37) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL18047923 | 0.85 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL7863108 | 0.85 | KMT2A (0.45) | KMT2ASMN1; SMN2STAT3ALDH1A1GAA | |
| SCHEMBL12246564 | 0.84 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2STAT3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |