Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR1B | P28222 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26961123 | 0.79 | FFAR4 (0.36) | — | |
| SCHEMBL20604957 | 0.78 | KDR (0.39) | HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL20604816 | 0.76 | ICMT (0.39) | HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL20604878 | 0.74 | DYRK1A (0.41) | — | |
| SCHEMBL20604847 | 0.70 | HASPIN (0.46) | HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL20604981 | 0.67 | GRIN2B (0.44) | — | |
| SCHEMBL20605488 | 0.65 | MCL1 (0.42) | — | |
| SCHEMBL20605078 | 0.65 | GRIN2B (0.48) | — | |
| SCHEMBL20605167 | 0.65 | ASH1L (0.33) | — | |
| SCHEMBL26581577 | 0.64 | ICMT (0.41) | HTR1AHTR1BDRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4292662-A2 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | Vanderbilt University (US) | 2023-12-20 | — | — | EP | disclosed |