Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 5/20 | 0.33 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.31 |
| ▸ | SMO | Q99835 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26967428 | 1.00 | FAAH (0.34) | FAAHBTKJAK2JAK3JAK1 | |
| SCHEMBL27123932 | 0.90 | BTK (0.35) | BTKJAK2JAK3JAK1TYK2 | |
| SCHEMBL26967316 | 0.90 | BTK (0.35) | BTKJAK2JAK3JAK1TYK2 | |
| SCHEMBL29141043 | 0.89 | USP30 (0.39) | JAK2JAK1CYP2C9 | |
| SCHEMBL29141026 | 0.89 | USP30 (0.39) | JAK2JAK1CYP2C9 | |
| SCHEMBL26967423 | 0.88 | BTK (0.34) | BTKJAK2JAK3JAK1TYK2 | |
| SCHEMBL29222093 | 0.85 | JAK1 (0.42) | BTKJAK2JAK3JAK1CYP2C9 | |
| SCHEMBL29222123 | 0.82 | KRAS (0.33) | — | |
| SCHEMBL29222268 | 0.81 | USP30 (0.40) | CYP2C9 | |
| SCHEMBL25251739 | 0.81 | PIK3CD (0.36) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294799-A2 | COMPOSITIONS AND METHODS FOR INHIBITION OF RAS | Theras Inc. (US) | 2023-12-27 | — | — | EP | disclosed |