⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23068576 | 0.97 | — | — | |
| SCHEMBL30607036 | 0.97 | — | — | |
| SCHEMBL22734114 | 0.97 | — | — | |
| SCHEMBL22734118 | 0.94 | — | — | |
| SCHEMBL29576569 | 0.81 | LATS1 (0.32) | — | |
| SCHEMBL22734106 | 0.80 | GAA (0.37) | — | |
| SCHEMBL30639341 | 0.78 | LATS1 (0.32) | — | |
| SCHEMBL30639342 | 0.78 | LATS1 (0.32) | — | |
| SCHEMBL31571836 | 0.78 | LATS1 (0.32) | — | |
| SCHEMBL14734142 | 0.78 | LATS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724195-B1 | SUBSTITUTED TETRAHYDROPYRAN DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | UNION THERAPEUTICS AS (DK) | 2023-12-27 | — | — | EP | disclosed |