SCHEMBL26968909

SCHEMBL26968909

[O-][S@+]1CCc2nc(N3CC(c4ccccc4)C3)nc(NC3CSC3)c21

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PDE4D Q08499 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30607010 0.86 PDE4D (0.43) PDE4D
SCHEMBL23068563 0.86 PDE4D (0.43) PDE4D
SCHEMBL23068562 0.86 PDE4D (0.43) PDE4D
SCHEMBL23068587 0.86 PDE4D (0.47) PDE4D
SCHEMBL30607013 0.86 PDE4D (0.47) PDE4D
SCHEMBL23068586 0.86 PDE4D (0.47) PDE4D
SCHEMBL30607024 0.84 PDE4D (0.44) PDE4D
SCHEMBL23068578 0.84 PDE4D (0.44) PDE4D
SCHEMBL23068579 0.84 PDE4D (0.44) PDE4D
SCHEMBL23068589 0.82 PDE4D (0.57) PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724194-B1 SUBSTITUTED AZETIDINE DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS UNION THERAPEUTICS AS (DK) 2023-12-27 — — EP claimed
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