Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 8/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23068586 | 1.00 | PDE4D (0.47) | PDE4DTNFPDE10AEGLN1NAPEPLD | |
| SCHEMBL23068587 | 1.00 | PDE4D (0.47) | PDE4DTNFPDE10AEGLN1NAPEPLD | |
| SCHEMBL12921249 | 0.91 | PDE4D (0.41) | PDE4DPDE10AEGLN1NAPEPLDCCR4 | |
| SCHEMBL23068579 | 0.87 | PDE4D (0.44) | PDE4DNAPEPLDCCR4 | |
| SCHEMBL30607024 | 0.87 | PDE4D (0.44) | PDE4DNAPEPLDCCR4 | |
| SCHEMBL23068578 | 0.87 | PDE4D (0.44) | PDE4DNAPEPLDCCR4 | |
| SCHEMBL26968909 | 0.86 | PDE4D (0.42) | PDE4D | |
| SCHEMBL30607017 | 0.86 | PDE4D (0.43) | PDE4DTNFPDE10AEGLN1 | |
| SCHEMBL23068567 | 0.86 | PDE4D (0.43) | PDE4DTNFPDE10AEGLN1 | |
| SCHEMBL23068564 | 0.86 | PDE4D (0.43) | PDE4DTNFPDE10AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712502-B | Substituted azetidine dihydro-thienopyrimidines and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2023-10-27 | — | — | CN | claimed |
| CN-111712502-B | Substituted azetidine dihydro-thienopyrimidines and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2023-10-27 | — | — | CN | disclosed |