SCHEMBL2697119

SCHEMBL2697119

CC(O[Sn](C)(C)OC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.40
TAAR1 Q96RJ0 3/20 0.38
ADRA2A P08913 3/20 0.38
ADRA2C P18825 2/20 0.38
ADRA2B P18089 1/20 0.38
CYP2D6 P10635 2/20 0.37
LMNA P02545 2/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
AOC3 Q16853 4/20 0.36
CYP3A4 P08684 2/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
SMPD1 P17405 1/20 0.36
DRD1 P21728 1/20 0.36
TBXA2R P21731 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2347452 0.91 HCAR2 (0.38) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL2330109 0.86 HCAR2 (0.40) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL2325093 0.77 HCAR2 (0.38) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL2324419 0.77 HCAR2 (0.38) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL2343962 0.74 HCAR2 (0.36) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL198133 0.74 HCAR2 (0.45) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL464725 0.74 HCAR2 (0.45) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL2737141 0.72 THRB (0.45) HCAR2TAAR1ADRA2AADRA2CADRA2B
Phosphine SCHEMBL20897413 0.72 CYP2D6 (0.46) HCAR2TAAR1ADRA2AADRA2CADRA2B
SCHEMBL5442572 0.72 HCAR2 (0.44) HCAR2TAAR1ADRA2AADRA2CADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168812-B2 Process for producing alkyl tin alkoxide compound and process for producing carbonic acid ester using said compound ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-05-01 US disclosed