Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534073 | 0.98 | TDP1 (0.43) | TDP1HSD17B10 | |
| SCHEMBL10000053 | 0.93 | TDP1 (0.34) | TDP1CA2 | |
| SCHEMBL14378379 | 0.92 | TDP1 (0.41) | TDP1HSD17B10 | |
| SCHEMBL15982341 | 0.92 | TDP1 (0.37) | TDP1 | |
| SCHEMBL25523469 | 0.90 | TDP1 (0.36) | TDP1 | |
| SCHEMBL25523468 | 0.89 | TDP1 (0.42) | TDP1HSD17B10 | |
| SCHEMBL19286018 | 0.89 | TDP1 (0.38) | TDP1 | |
| SCHEMBL17243339 | 0.87 | TDP1 (0.37) | TDP1 | |
| Propene SCHEMBL4595094 | 0.87 | TDP1 (0.37) | TDP1 | |
| Propene SCHEMBL3275817 | 0.87 | TDP1 (0.37) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857603-B2 | PTH compounds with low peak-to-trough ratios | ASCENDIS PHARMA BONE DISEASES A/S (DK) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11857603-B2 | PTH compounds with low peak-to-trough ratios | PTH1R, PTMS, FGF23 | TDP1 4736/4885CA2 1335/4885HSD17B10 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.