SCHEMBL2697698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6340123	0.94	PTGS2 (0.80)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL980960	0.90	PDPK1 (1.00)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL981158	0.90	PDPK1 (1.00)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL6342351	0.89	PTGS2 (0.90)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL3240313	0.88	PTGS2 (1.00)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL6430302	0.88	PTGS2 (1.00)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL215932	0.88	PTGS2 (1.00)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL6344505	0.86	PTGS2 (0.83)	PDPK1PTGS2PTGS1CYP2C9PTGES
	SCHEMBL2697564	0.86	PTGS2 (0.65)	PDPK1PTGS2PTGS1CYP2C9CYP3A4
	SCHEMBL5923919	0.86	PDPK1 (1.00)	PDPK1PTGS2PTGS1CYP2C9PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.