Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL5605980 | 0.93 | KDM4E (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4261643 | 0.93 | KDM4E (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL5605972 | 0.93 | KDM4E (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL17889024 | 0.93 | KDM4E (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL26977489 | 0.93 | KMT2A (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL1833538 | 0.90 | KDM4E (0.63) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL1833542 | 0.90 | KDM4E (0.63) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28813398 | 0.89 | KDM4E (0.61) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL9397492 | 0.89 | KDM4E (0.61) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27901971 | 0.89 | KDM4E (0.61) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050513-A1 | COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING DISEASE CAUSED BY PROTEIN NITRATION COMPRISING PEPTIDE WITH TERMINAL TYROSINE AS EFFECTIVE COMPONENT | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2024-02-15 | — | — | US | disclosed |
| EP-4298924-A1 | COMPOSITION, FOR PREVENTING, RELIEVING, OR TREATING DISEASE CAUSED BY NITRATION OF PROTEIN, CONTAINING PEPTIDE HAVING TYROSINE LOCATED AT TERMINAL AS ACTIVE INGREDIENT | Industry-Academic Cooperation Foundation Gyeongsang National University (KR) | 2024-01-03 | — | — | EP | disclosed |
| CN-116916765-A | Composition for preventing, improving or treating diseases caused by protein nitrification comprising peptide having tyrosine at its end as active ingredient | 庆尚国立大学校 产学协力团 | 2023-10-20 | — | — | CN | disclosed |