SCHEMBL26985243

SCHEMBL26985243

CC(C)(C)OC(=O)N1CCCC(c2ccc(Br)c(F)c2)C1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PDE4B Q07343 1/20 0.52
▸ TRPV3 Q8NET8 2/20 0.48
▸ HRH3 Q9Y5N1 4/20 0.46
▸ BCL9 O00512 2/20 0.45
▸ CTNNB1 P35222 2/20 0.45
▸ FPR2 P25090 1/20 0.43
▸ USP30 Q70CQ3 2/20 0.43
▸ HPGDS O60760 1/20 0.43
▸ SCN9A Q15858 2/20 0.42
▸ JAK2 O60674 1/20 0.42
▸ JAK1 P23458 1/20 0.42
▸ DPP4 P27487 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30722047 1.00 PDE4B (0.52) PDE4BTRPV3HRH3BCL9CTNNB1
SCHEMBL26985427 0.94 PDE4B (0.58) PDE4BTRPV3HRH3USP30DPP4
SCHEMBL25251089 0.89 USP30 (0.48) PDE4BHRH3USP30DPP4
SCHEMBL26985167 0.87 NAMPT (0.51) PDE4BTRPV3HRH3DPP4MAPT
SCHEMBL24196363 0.86 PDE4B (0.52) PDE4BTRPV3HRH3BCL9CTNNB1
SCHEMBL21962362 0.86 PDE4B (0.49) PDE4BTRPV3HRH3BCL9CTNNB1
SCHEMBL14225752 0.85 PDE4B (0.53) PDE4BTRPV3BCL9CTNNB1FPR2
SCHEMBL15650585 0.85 PDE4B (0.53) PDE4BTRPV3HRH3BCL9CTNNB1
SCHEMBL31386180 0.84 PDE4B (0.52) PDE4BTRPV3HRH3BCL9CTNNB1
SCHEMBL22810473 0.83 PDE4B (0.52) PDE4BTRPV3USP30HPGDSJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 — — US disclosed
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-09-02 — — US disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 — — EP disclosed
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 — — EP disclosed
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-24 — — US disclosed
WO-2024010761-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
WO-2024010761-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 PDE4B 3361/4885TRPV3 4792/4885HRH3 4838/4885
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 PDE4B 3361/4885TRPV3 4792/4885HRH3 4838/4885
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 PDE4B 3361/4885TRPV3 4792/4885HRH3 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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