SCHEMBL26985367

SCHEMBL26985367

Nc1nc(Cl)nc(NCC(=O)O)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.52
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
CA9 Q16790 6/20 0.52
CA14 Q9ULX7 6/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA7 P43166 2/20 0.52
CA13 Q8N1Q1 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
PDE4A P27815 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
PLAU P00749 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
GRIN2D O15399 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1870258 0.87 CA1 (0.49) CA12CA1CA2CA9CA14
SCHEMBL15440765 0.87 CYP1A2 (0.48) CA12CA1CA2CA9CA14
SCHEMBL9438755 0.87 CA12 (0.59) CA12CA1CA2CA9CA14
SCHEMBL4292023 0.87 CA12 (0.55) CA12CA1CA2CA9CA14
Water SCHEMBL11190091 0.85 CA12 (0.54) CA12CA1CA2CA9CA14
SCHEMBL26985249 0.80 CA1 (0.41) CA12CA1CA2CA9CA14
SCHEMBL134610 0.79 LMNA (0.68) CA12CA1CA2CA9CA14
SCHEMBL721907 0.76 CA12 (0.51) CA12CA1CA2CA9CA14
SCHEMBL11374223 0.75 LMNA (0.45) CA12CA1CA2CA9CA14
SCHEMBL2436900 0.75 GAA (0.61) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551210-A1 BIFACIAL PEPTIDE NUCLEIC ACID PROBES AND METHODS OF USING THEREOF Ohio State Innovation Foundation (US) 2025-05-14 EP disclosed
WO-2024010977-A1 BIFACIAL PEPTIDE NUCLEIC ACID PROBES AND METHODS OF USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-01-11 WO disclosed