Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172831 | 1.00 | SPHK1 (0.48) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL10185778 | 1.00 | SPHK1 (0.48) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL18464396 | 1.00 | SPHK1 (0.48) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL172766 | 1.00 | SPHK1 (0.48) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL28842476 | 1.00 | SPHK1 (0.48) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL12566014 | 1.00 | SPHK1 (0.48) | SPHK1CA1SPHK2OPRM1ACE2 | |
| Hydrochloric Acid SCHEMBL4779651 | 0.98 | SPHK1 (0.47) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL27863219 | 0.98 | CA1 (0.50) | SPHK1CA1SPHK2OPRM1ACE2 | |
| SCHEMBL23197652 | 0.91 | — | — | |
| SCHEMBL8296936 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250263751-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCED TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | LIFE TECHNOLOGIES CORP (US) | 2025-08-21 | — | — | US | disclosed |
| US-20250109412-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCED TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | LIFE TECHNOLOGIES CORP (US) | 2025-04-03 | — | — | US | disclosed |
| US-12152248-B2 | Membrane-penetrating peptides to enhanced transfection and compositions and methods for using same | Life Technologies Corporation (US) | 2024-11-26 | — | — | US | disclosed |
| US-20200392537-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCED TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | Life Technologies Corporation | 2020-12-17 | — | — | US | disclosed |
| US-10760098-B2 | Membrane-penetrating peptides to enhance transfection and compositions and methods for using same | Life Technologies Corporation (US) | 2020-09-01 | — | — | US | disclosed |
| US-20190203196-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS | Life Technologies Corporation | 2019-07-04 | — | — | US | disclosed |
| US-20180163231-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | Life Technologies Corporation | 2018-06-14 | — | — | US | disclosed |
| US-20180073009-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS | Life Technologies Corporation | 2018-03-15 | — | — | US | disclosed |
| US-9856496-B2 | Membrane-penetrating peptides to enhance transfection and compositions and methods for using same | Life Technologies Corporation (US) | 2018-01-02 | — | — | US | disclosed |
| EP-3079723-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | Life Technologies Corporation (US) | 2016-10-19 | — | — | EP | disclosed |
| US-20150211021-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | Life Technologies Corporation | 2015-07-30 | — | — | US | disclosed |
| WO-2015089487-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | Life Technologies Corporation (US) | 2015-06-18 | — | — | WO | disclosed |
| US-20140142290-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEICACIDS | Life Technologies Corporation (US) | 2014-05-22 | — | — | US | disclosed |
| US-20120108804-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS | Life Technologies Corporation (US) | 2012-05-03 | — | — | US | disclosed |
| US-20090197307-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS | INVITROGEN CORPORATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-20060257858-A1 | Methods and compositions for introducing biopolymers into cells | INVITROGEN CORPORATION (US) | 2006-11-16 | — | — | US | disclosed |
| US-20050054847-A1 | Compositions and methods for preparing short RNA molecules and other nucleic acids | INVITROGEN CORPORATION (US) | 2005-03-10 | — | — | US | disclosed |
| EP-1242609-A2 | NOVEL COLLOID SYNTHETIC VECTORS FOR GENE THERAPY | Novartis AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049324-A2 | NOVEL COLLOID SYNTHETIC VECTORS FOR GENE THERAPY | NOVARTIS AG (CH) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197307-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS | NSUN3, EFTUD2, AGO2 | SPHK1 661/4885CA1 4712/4885SPHK2 854/4885 |
| US-20200392537-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCED TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | SLC7A1, NPC1, NPC1L1 | SPHK1 2599/4885CA1 2451/4885SPHK2 2228/4885 |
| US-10760098-B2 | Membrane-penetrating peptides to enhance transfection and compositions and methods for using same | SLC7A1, NPC1, NPC1L1 | SPHK1 2586/4885CA1 2462/4885SPHK2 2241/4885 |
| US-12152248-B2 | Membrane-penetrating peptides to enhanced transfection and compositions and methods for using same | SLC7A1, NPC1, NPC1L1 | SPHK1 2599/4885CA1 2451/4885SPHK2 2228/4885 |
| US-20180163231-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | SLC7A1, NPC1, NPC1L1 | SPHK1 2586/4885CA1 2462/4885SPHK2 2241/4885 |
| US-20120108804-A1 | COMPOSITIONS AND METHODS FOR PREPARING SHORT RNA MOLECULES AND OTHER NUCLEIC ACIDS | NSUN3, EFTUD2, AGO2 | SPHK1 661/4885CA1 4712/4885SPHK2 854/4885 |
| US-20250109412-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCED TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | SLC7A1, NPC1, NPC1L1 | SPHK1 2599/4885CA1 2451/4885SPHK2 2228/4885 |
| US-20150211021-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCE TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | SLC7A1, NPC1, NPC1L1 | SPHK1 2586/4885CA1 2462/4885SPHK2 2241/4885 |
| US-20250263751-A1 | MEMBRANE-PENETRATING PEPTIDES TO ENHANCED TRANSFECTION AND COMPOSITIONS AND METHODS FOR USING SAME | SLC7A1, NPC1, NPC1L1 | SPHK1 2599/4885CA1 2451/4885SPHK2 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.