⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428440 | 0.67 | — | — | |
| SCHEMBL208575 | 0.64 | — | — | |
| SCHEMBL6251728 | 0.62 | — | — | |
| SCHEMBL293653 | 0.62 | — | — | |
| SCHEMBL4835428 | 0.61 | — | — | |
| SCHEMBL3895041 | 0.61 | — | — | |
| SCHEMBL9407380 | 0.61 | — | — | |
| SCHEMBL10840976 | 0.61 | — | — | |
| SCHEMBL137444 | 0.59 | — | — | |
| SCHEMBL10425783 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111432815-A | Enhancing cancer treatment efficacy via sphingosine-1-phosphate pathway | AC生物科学公司 | 2020-07-17 | — | — | CN | claimed |
| EP-0126344-A2 | Tripeptide esters of therapeutic agents | ABBOTT LABORATORIES (US) | 1984-11-28 | — | — | EP | claimed |
| US-20210395189-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2021-12-23 | — | — | US | disclosed |
| EP-3812372-A2 | 7-HETEROCYCLYL SUBSTITUTED SANCYCLINE DERIVATIVES FOR TREATING BACTERIAL, VIRAL AND PARASITIC INFECTIONS (E.G. MALARIA) OR INFLAMMATORY DISEASES | Paratek Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| CN-111432815-A | Enhancing cancer treatment efficacy via sphingosine-1-phosphate pathway | AC生物科学公司 | 2020-07-17 | — | — | CN | disclosed |
| EP-3045449-A1 | TETRACYCLINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS | Paratek Pharmaceuticals, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| US-20160046561-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2016-02-18 | — | — | US | disclosed |
| US-9012433-B2 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-20130102779-A1 | Substituted Tetracycline Compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2013-04-25 | — | — | US | disclosed |
| US-8318706-B2 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2455367-A1 | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections | Paratek Pharmaceuticals, Inc. (US) | 2012-05-23 | — | — | EP | disclosed |
| EP-0863878-B1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1255727-A1 | ACETAL HYDROXYLAMINE COMPOUNDS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060785-A1 | ACETAL HYDROXYLAMINE COMPOUNDS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |
| US-5962469-A | PREVENTION OF OXIDATION TISSUE DAMAGE BY FREE RADICALS | HOECHST MARION ROUSSEL INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0863878-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010218-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-20 | — | — | WO | disclosed |
| EP-0280610-B1 | DIPEPTIDES, PREPARATION PROCESS AND USE IN DOSING PROTEASES | SERBIO (FR) | 1992-10-21 | — | — | EP | disclosed |
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |