Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17275263 | 0.89 | GPR119 (0.56) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL21659296 | 0.87 | MAPT (0.57) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL31715968 | 0.86 | MAPT (0.53) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL21659187 | 0.83 | MAPT (0.60) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL23868398 | 0.82 | MAPT (0.58) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL21659378 | 0.82 | MAPT (0.58) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL22776398 | 0.82 | MAPT (0.58) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL21659380 | 0.81 | MAPT (0.55) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL22638159 | 0.81 | KIT (0.65) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL21659329 | 0.81 | MAPT (0.57) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010810-A2 | FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF | CIDARA THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |