Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 16/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22628718 | 0.90 | LMNA (0.64) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL22215103 | 0.90 | LMNA (0.64) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL23330708 | 0.90 | LMNA (0.64) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL24452562 | 0.90 | LMNA (0.64) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL19370225 | 0.90 | LMNA (0.64) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL24452563 | 0.90 | LMNA (0.64) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL26428753 | 0.86 | LMNA (0.45) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL19366706 | 0.86 | LMNA (0.45) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL24645801 | 0.84 | LMNA (0.49) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL22632318 | 0.83 | LMNA (0.44) | LMNATP53ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010810-A2 | FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF | CIDARA THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |