Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.47 |
| ▸ | JAK2 | O60674 | 12/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26987136 | 0.89 | JAK1 (0.46) | JAK1JAK2KCNH2 | |
| SCHEMBL30756723 | 0.89 | JAK1 (0.46) | JAK1JAK2KCNH2 | |
| SCHEMBL31347584 | 0.88 | JAK1 (0.53) | JAK1JAK2KCNH2 | |
| SCHEMBL27043851 | 0.87 | JAK1 (0.49) | JAK1JAK2KCNH2 | |
| SCHEMBL26987570 | 0.86 | JAK1 (0.54) | JAK1JAK2KCNH2 | |
| SCHEMBL30756867 | 0.86 | JAK1 (0.54) | JAK1JAK2KCNH2 | |
| SCHEMBL31347560 | 0.86 | JAK1 (0.51) | JAK1JAK2KCNH2 | |
| SCHEMBL30756821 | 0.84 | CLK1 (0.46) | JAK1JAK2KCNH2 | |
| SCHEMBL26987746 | 0.84 | CLK1 (0.46) | JAK1JAK2KCNH2 | |
| SCHEMBL30757290 | 0.83 | JAK1 (0.43) | JAK1JAK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024009215-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-11 | — | — | WO | disclosed |