Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30746561 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL26985012 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL30746537 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL30746641 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL26984983 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL26985292 | 0.77 | TP53 (0.40) | MAPTKMT2ALMNAGAAL3MBTL1 | |
| SCHEMBL30746459 | 0.77 | TP53 (0.40) | MAPTKMT2ALMNAGAAL3MBTL1 | |
| SCHEMBL34463286 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL30746472 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A | |
| SCHEMBL26985182 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTRBM39SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |