Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269912 | 0.89 | ALOX15 (0.39) | TSHRALOX15 | |
| SCHEMBL1998669 | 0.85 | ALOX15 (0.36) | TSHRALOX15 | |
| SCHEMBL277071 | 0.78 | TSHR (0.54) | TSHRALOX15 | |
| SCHEMBL270121 | 0.74 | — | — | |
| SCHEMBL277008 | 0.74 | TSHR (0.45) | TSHRALOX15ALDH1A1MAPK1 | |
| SCHEMBL277018 | 0.74 | TSHR (0.50) | TSHRALOX15ALDH1A1 | |
| SCHEMBL2975886 | 0.73 | TSHR (0.30) | TSHR | |
| SCHEMBL315034 | 0.73 | TSHR (0.33) | TSHRALOX15ALDH1A1MAPK1TDP1 | |
| SCHEMBL277272 | 0.72 | TSHR (0.48) | TSHRALOX15 | |
| SCHEMBL8899980 | 0.72 | ALOX15 (0.34) | TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027351-B1 | PHENANTHROLINE DERIVATIVES | FIBROGEN INC (US) | 2003-12-03 | — | — | EP | claimed |
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1999021860-B1 | PHENANTHROLINE DERIVATIVES | FIBROGEN INC (US) | 1999-08-05 | — | — | WO | claimed |
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | claimed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | claimed |
| US-5623082-A | REACTING CARBOXYLIC ACID OR ITS ANHYDRIDE WITH CARBONYL CHLORIDE IN PRESENCE OF DI-SEC-BUTYLFORMAMIDE OR DI-3-PENTYLFORMAMIDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | claimed |
| US-5347047-A | Phosgene | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | claimed |
| EP-0601414-A1 | Process for the preparation of acylated aromatics | BASF Aktiengesellschaft (DE) | 1994-06-15 | — | — | EP | claimed |
| EP-0230224-B1 | PROCESS FOR THE PREPARATION OF ALCOXYCARBONYL ISOCYANATES | BAYER AG (DE) | 1991-07-17 | — | — | EP | claimed |
| US-4777283-A | Process for the preparation of alkoxycarbonyl isocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | claimed |
| EP-0230224-A2 | Process for the preparation of alcoxycarbonyl isocyanates | BAYER AG (DE) | 1987-07-29 | — | — | EP | claimed |
| CN-113376963-B | Coloring composition and compound | 住友化学株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-113376962-B | Coloring composition and compound | 住友化学株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-113376965-B | Coloring composition and compound | 住友化学株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-113376964-B | Coloring composition and compound | 住友化学株式会社 | 2024-04-26 | — | — | CN | disclosed |
| EP-0475158-A2 | Use of alpha aryl acrylic acid derivatives for pest control | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0230224-B1 | PROCESS FOR THE PREPARATION OF ALCOXYCARBONYL ISOCYANATES | BAYER AG (DE) | 1991-07-17 | — | — | EP | disclosed |
| EP-0340706-A2 | Process for the preparation of carboxylic-acid chlorides | BASF Aktiengesellschaft (DE) | 1989-11-08 | — | — | EP | disclosed |
| US-4777283-A | Process for the preparation of alkoxycarbonyl isocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | disclosed |
| EP-0230224-A2 | Process for the preparation of alcoxycarbonyl isocyanates | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |