Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 17/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005451 | 1.00 | MAPK14 (0.47) | MAPK14KDM1AARCYP11B1CYP11B2 | |
| SCHEMBL27005453 | 1.00 | MAPK14 (0.47) | MAPK14KDM1AARCYP11B1CYP11B2 | |
| SCHEMBL27010012 | 0.90 | MAPK14 (0.52) | MAPK14KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27005355 | 0.88 | KDM1A (0.52) | KDM1A | |
| SCHEMBL27006613 | 0.88 | KDM1A (0.52) | KDM1A | |
| SCHEMBL27009755 | 0.88 | KDM1A (0.52) | KDM1A | |
| SCHEMBL27005351 | 0.88 | KDM1A (0.52) | KDM1A | |
| SCHEMBL27005183 | 0.85 | KDM1A (0.52) | KDM1A | |
| SCHEMBL27005427 | 0.85 | KDM1A (0.52) | KDM1A | |
| SCHEMBL27005433 | 0.85 | KDM1A (0.52) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |