Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 17/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005451 | 0.90 | MAPK14 (0.47) | MAPK14KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27005453 | 0.90 | MAPK14 (0.47) | MAPK14KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27005189 | 0.90 | MAPK14 (0.47) | MAPK14KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27004944 | 0.85 | KDM1A (0.61) | MAPK14KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27005356 | 0.84 | KDM1A (0.58) | KDM1A | |
| SCHEMBL27010007 | 0.84 | KDM1A (0.53) | MAPK14KDM1ACYP11B1CYP11B2PDE4A | |
| SCHEMBL27005431 | 0.81 | KDM1A (0.60) | KDM1A | |
| SCHEMBL27005812 | 0.81 | KDM1A (0.63) | MAPK14KDM1ACYP11B1CYP11B2PDE4A | |
| SCHEMBL27004945 | 0.81 | KDM1A (0.56) | MAPK14KDM1A | |
| SCHEMBL27005539 | 0.78 | KDM1A (0.51) | KDM1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |