Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPM1 | P06748 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339190 | 0.87 | TLR8 (0.40) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL29709725 | 0.84 | HDAC8 (0.36) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL24508511 | 0.84 | HDAC8 (0.36) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL11890643 | 0.84 | TLR8 (0.44) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL27004838 | 0.82 | TLR8 (0.38) | TLR8NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29083592 | 0.81 | TLR8 (0.37) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL27006292 | 0.81 | TLR8 (0.36) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL21810482 | 0.80 | TLR8 (0.36) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL27007121 | 0.79 | TLR8 (0.41) | HDAC8TLR8NPC1RAB9AALDH1A1 | |
| SCHEMBL27007126 | 0.78 | TLR8 (0.36) | HDAC8TLR8NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |