Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701835 | 0.88 | L3MBTL3 (0.46) | SMN1; SMN2USP2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL17465245 | 0.84 | L3MBTL3 (0.51) | SMN1; SMN2USP2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL22315605 | 0.83 | L3MBTL3 (0.33) | SMN1; SMN2USP2L3MBTL3L3MBTL1RIPK1 | |
| SCHEMBL18702083 | 0.83 | L3MBTL3 (0.40) | L3MBTL3L3MBTL1RIPK1 | |
| SCHEMBL18702298 | 0.82 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1RIPK1DPP4 | |
| SCHEMBL4550274 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL3L3MBTL1PIK3CAALDH1A1 | |
| SCHEMBL27979097 | 0.79 | MEN1 (0.48) | SMN1; SMN2L3MBTL3L3MBTL1RECQLMCHR1 | |
| SCHEMBL800634 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2USP2L3MBTL1ALDH1A1CA12 | |
| SCHEMBL8749086 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2USP2L3MBTL1ALDH1A1CA12 | |
| SCHEMBL11890344 | 0.78 | KDM4E (0.38) | SMN1; SMN2USP2L3MBTL3L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018151-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC | 2024-01-18 | — | — | US | disclosed |
| US-20240018151-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018151-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | PIKFYVE, PIK3CD, PIK3R5 | SMN1; SMN2 3216/4885USP2 1986/4885L3MBTL3 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.