Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17665098 | 0.81 | ADRB1 (0.45) | AKR1C3HSD17B10KMT2AUSP2MAPT | |
| SCHEMBL14862589 | 0.80 | AKR1C3 (0.44) | AKR1C3TSHRMMP2MMP13ADAMTS5 | |
| SCHEMBL17642585 | 0.79 | AKR1C3 (0.39) | AKR1C3HDAC4ALDH1A1FAAHMGLL | |
| SCHEMBL1393084 | 0.79 | MAPT (0.48) | HSD17B10KMT2AUSP2HDAC4MAPT | |
| SCHEMBL20457968 | 0.76 | KDM4E (0.50) | TSHRHSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL17660598 | 0.76 | MEN1 (0.44) | TSHRKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL20956904 | 0.76 | AKR1C3 (0.37) | AKR1C3TSHRMMP2MMP13ADAMTS5 | |
| SCHEMBL16177759 | 0.74 | AKR1C3 (0.37) | AKR1C3TSHRMMP2MMP13HSD17B10 | |
| SCHEMBL23199735 | 0.73 | AKR1C3 (0.42) | AKR1C3TSHRMMP2MMP13ADAMTS5 | |
| SCHEMBL21812427 | 0.72 | GRIN2D (0.45) | AKR1C3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |