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Sugi Predict / Compounds / SCHEMBL27010353

SCHEMBL27010353

SCHEMBL27010353

CNN(CC(C)(C)O)c1ccc(-c2sc(C(=O)N3CCC[C@@H](N(C)C(=O)OC(C)(C)C)C3)cc2-c2ccc(C#N)c(F)c2)cc1N

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 19/20 0.39
▸ GPR119 Q8TDV5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27009209 0.91 KDM1A (0.38) KDM1AGPR119
SCHEMBL27005422 0.88 KDM1A (0.44) KDM1A
SCHEMBL27010350 0.81 GPR119 (0.45) KDM1AGPR119
SCHEMBL27009742 0.80 GPR119 (0.41) KDM1AGPR119
SCHEMBL27009922 0.80 KDM1A (0.44) KDM1AGPR119
SCHEMBL27010455 0.80 GPR119 (0.42) KDM1AGPR119
SCHEMBL27007959 0.79 KDM1A (0.46) KDM1A
SCHEMBL27005157 0.78 KDM1A (0.46) KDM1A
SCHEMBL27009974 0.77 KDM1A (0.40) KDM1AGPR119
SCHEMBL27010287 0.77 KDM1A (0.46) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306520-A1 THIOPHENE COMPOUND AND APPLICATION THEREOF Medshine Discovery Inc. (CN) 2024-01-17 — — EP disclosed