SCHEMBL2701154

SCHEMBL2701154

CCCCCCCC/C=C\CCCCCCCCO[C](CC)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.53
LPAR3 Q9UBY5 3/20 0.53
LPAR1 Q92633 2/20 0.53
FAAH O00519 1/20 0.53
NAAA Q02083 1/20 0.48
EPHX2 P34913 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246012 0.87 NAAA (0.60) FAAHNAAA
SCHEMBL887113 0.87 NAAA (0.60) FAAHNAAA
SCHEMBL391505 0.87 NAAA (0.60) FAAHNAAA
SCHEMBL931393 0.87 NAAA (0.60) FAAHNAAA
SCHEMBL6436754 0.81 NAAA (0.78) FAAHNAAAEPHX2
SCHEMBL3892454 0.81 NAAA (0.78) FAAHNAAAEPHX2
SCHEMBL28181854 0.81 NAAA (0.78) FAAHNAAAEPHX2
SCHEMBL28181872 0.81 NAAA (0.78) FAAHNAAAEPHX2
SCHEMBL3892460 0.81 NAAA (0.78) FAAHNAAAEPHX2
SCHEMBL11094238 0.81 NAAA (0.78) FAAHNAAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2192127-B1 Haemophilus influenzae type IV Pili NATIONWIDE CHILDREN S HOSPITAL INC (US) 2012-05-09 EP disclosed
EP-1904519-B1 CHIMERIC VACCINE FOR HAEMOPHILUS INFLUENZAE-INDUCED DISEASE NATIONWIDE CHILDRENS HOSPITAL (US) 2010-11-17 EP disclosed
EP-2192127-A1 Haemophilus influenzae type IV Pili Nationwide Children's Hospital, Inc. (US) 2010-06-02 EP disclosed
EP-1697403-B1 HAEMOPHILUS INFLUENZAE TYPE IV PILI NATIONWIDE CHILDRENS HOSPITAL (US) 2010-03-24 EP disclosed
EP-2070945-A1 Genes of an otitis media isolate of nontypeable haemophilus influenzae Nationwide Children's Hospital, Inc. (US) 2009-06-17 EP disclosed
EP-1923399-A1 Genes of an otitis media isolate of nontypeable Haemophilus influenzae CHILDREN'S HOSPITAL, INC. (US) 2008-05-21 EP disclosed
EP-1904519-A2 CHIMERIC VACCINE FOR HAEMOPHILUS INFLUENZAE-INDUCED DISEASE CHILDREN'S HOSPITAL, INC. (US) 2008-04-02 EP disclosed
EP-1899366-A2 GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HAEMOPHILUS INFLUENZAE CHILDREN'S HOSPITAL, INC. (US) 2008-03-19 EP disclosed
WO-2008011344-A2 DISRUPTION OF PROGRAMMED DEATH-1 (PD-1) LIGANDS TO ADJUVANT ADENO-ASSOCIATED VIRUS VECTOR VACCINES NATIONWIDE CHILDREN'S HOSPITAL INC. (US) 2008-01-24 WO disclosed
WO-2007008527-A2 CHIMERIC VACCINE FOR HAEMOPHILUS INFLUENZAE-INDUCED DISEASE CHILDREN'S HOSPITAL INC. (US) 2007-01-18 WO disclosed
EP-1601688-A2 GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HAEMOPHILUS INFLUENZAE CHILDREN'S HOSPITAL, INC. (US) 2005-12-07 EP disclosed
WO-2005063802-A2 HAEMOPHILUS INFLUENZAE TYPE IV PILI CHILDREN'S HOSPITAL, INC. (US) 2005-07-14 WO disclosed
WO-2004078949-A2 GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HAEMOPHILUS INFLUENZAE CHILDREN'S HOSPITAL, INC. (US) 2004-09-16 WO disclosed
EP-1019021-A1 STABILIZED PREPARATIONS FOR USE IN METERED DOSE INHALERS Inhale Therapeutic Systems, Inc. (US) 2000-07-19 EP disclosed
EP-1019023-A1 STABILIZED PREPARATIONS FOR USE IN NEBULIZERS Inhale Therapeutic Systems, Inc. (US) 2000-07-19 EP disclosed
EP-1019022-A1 PERFORATED MICROPARTICLES AND METHODS OF USE Inhale Therapeutic Systems, Inc. (US) 2000-07-19 EP disclosed
WO-1999016419-A9 PERFORATED MICROPARTICLES AND METHODS OF USE ALLIANCE PHARMA (US) 1999-08-19 WO disclosed
WO-1999016422-A1 STABILIZED PREPARATIONS FOR USE IN METERED DOSE INHALERS INHALE THERAPEUTIC SYSTEMS, INC. (US) 1999-04-08 WO disclosed
WO-1999016420-A1 STABILIZED PREPARATIONS FOR USE IN NEBULIZERS INHALE THERAPEUTIC SYSTEMS, INC. (US) 1999-04-08 WO disclosed
WO-1999016419-A1 PERFORATED MICROPARTICLES AND METHODS OF USE INHALE THERAPEUTIC SYSTEMS, INC. (US) 1999-04-08 WO disclosed